In this research, a three-dimensional model of a radiator was created using SolidWorks software. The effects of adding hybrid nanoparticles to the coolant base fluid on the thermo-physical properties of the nanofluid and the radiator thermal function were investigated through modeling and experimentation. The nanoparticles used in this research consist of Al2O3 and SiC in four various mass levels, including 1%Al2O3+4%SiC, 2%Al2O3+3%SiC, 3%Al2O3+2%SiC, and 4%Al2O3+1%SiC, which were defined and modeled. The results showed that adding the nanoparticles to the fluid causes an increase in viscosity, density, and heat transfer coefficient in the base fluid such that for the hynanofluid 4%Al2O3+1%SiC, the maximum density, heat transfer coefficient, and the best function is seen for fluid cooling, but the viscosity values among various samples do not differ considerably. Also, the results showed that adding the nanoparticles and creating the nanofluid in the radiator design causes consistency in the radiator output temperature, which represents a significant improvement in the radiator's thermal function. The experimental results showed that by adding nanoparticles to the base fluid, the temperatures of the fluids entering and pouring out of the radiator, and the temperature of the air passing over the radiator fins increase, decrease, and increase, respectively.