نویسندگان
1 گروه مهندسی شیمی، دانشکده نفت و پتروشیمی، دانشگاه حکیم سبزواری
2 گروه مهندسی شیمی، دانشکده مهندسی، دانشگاه فردوسی مشهد
3 گروه فارماسیوتیکس، مرکز تحقیقات بیوتکنولوژی و نانوتکنولوژی دانشکده داروسازی دانشگاه علوم پزشکی مشهد
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
First of all, two medical nanofluids containing single-walled carbon nanotube as nano-platform with loaded MF1 and conjugated MF2 anticancer drug cisplatin were prepared and thermal characteristics of these nanofluids were surveyed. The thermal property of nanofluid can play an important role on drug release of cisplatin in target region especially cancerous tumors. Due to different bonds of cisplatin on carbon nanotubes, thermal property of nanofluids were completely different which were checked using thermal conductivity. Results show a significant change of thermal conductivity during dialysis of MF2 nanofluid because of the entrapped cisplatin release inside carbon nanotubes. This shows the important role of cisplatin as a thermal drug to increase of drug efficacy and reduce the drug side effects especially for cancer treatment.
کلیدواژهها [English]