In this paper, by choosing chlorobenzene (CB) and diethyl ether (DEE) as antisolvents, the effect of changing the antisolvent on the morphology, optical and structural properties of CH3NH3PbI3 perovskite and the performance of perovskite solar cell (PSC) with the structure FTO/Compact TiO2/Mesoporous TiO2/CH3NH3PbI3/CuInS2/Au was investigated. The direct optical bandgap for the perovskite with CB and DEE antisolvents was calculated 1.579 and 1.595 eV, respectively, and for both samples the indirect optical bandgap was 56 meV lower than the direct bandgap. The Urbach energy for the perovskite with CB and DEE antisolvents was obtained 0.085 and 0.089 eV, respectively, which indicated fewer interband defect states for the sample with CB antisolvent. The parameters of crystallite size, unit cell volume, dislocation density and microstrain for the perovskite with CB antisolvent were obtained 66.53 nm, 1083.249 Å3, 2.25 × 10-4 and 2.69 × 10-3, respectively, which compared to the values of these parameters in the sample with DEE antisolvent (63.59 nm, 1083.684 Å3, 2.47 × 10-4 and 2.84 × 10-3, respectively), indicating higher quality and fewer lattice defects. Finally, PSC with CB antisolvent showed an efficiency of 10.89%, which was about 19% higher than the efficiency of PSC with DEE antisolvent (9.16%). The results of this research can be used in the optical and structural optimization of the perovskite layer to manufacture efficient perovskite solar cells.